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CENP-A Antibody: HRP

SKU: orb148112
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特色特色

描述

Mouse monoclonal to CENP-A (HRP). A replicated chromosome includes two kinetochores that control chromosome segregation during mitosis. The Centromere Protein-A, CENP-A, is a Histone H3-like protein that contains a C-terminal H3-like domain, which is required for centromere localization of CENP-A, and an antigenic N-terminal domain. CENP-A, originally isolated from HeLa cells, is essential for kinetochore targeting of CENP-C. In the presence of DNA CENP-A forms an octa-meric complex with histones H4, H2A, H2B. CENP-A specifically localizes to active centromeres and is a component of specialized centromeric nucleosomes, on which kinetochores are assembled. CENP-A is essential for nucleosomal packaging of centromeric DNA at interphase and functions as a centromere formation marker on the chromosome..

研究领域

Product Categories/Products/Antibodies,Product Categories/Research Area,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Infectious Diseases,Cell Signaling | Epigenetics and Nuclear Signaling

图片与验证

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已测应用ELISA, IHC, WB
稀释范围WB (1:1000), ICC/IF (1:100)
反应性Human
应用说明
1 µg/ml of SMC-202 was sufficient for detection of CENPA in 20 µg of U2OS cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

关键属性

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宿主Mouse
克隆性Monoclonal
同种型IgG1
克隆号5A7-2E11
免疫原Synthetic peptide corresponding to a portion of human CENP-A
靶点CENPA
分子量18kDa
偶联HRP

储存与操作

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储存Conjugated antibodies should be stored according to the product label
缓冲液/防腐剂73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide and 0.23mM Citrate in dH2O
浓度1 mg/ml
有效期12 months from date of receipt.
免责声明For research use only

别名

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CENP A antibody, cenpa antibody, Centromere auto antigen A antibody, Histone H3 like centromeric protein A antibody

相似产品

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质量保证

质量保证

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常用数据库链接

基因符号
CENPA
UniProt
P49450
NCBI 基因 ID
1058
RefSeq（蛋白）：NP_001035891.1

UniProt 详情

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暂无 UniProt 数据

NCBI 基因详情

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暂无 NCBI 基因数据

NCBI 参考序列

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相关登录号
基因转录本和蛋白产物的整理参考序列
蛋白NP_001035891.1

实验方案信息

WB
免疫印迹（WB）
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IHC
免疫组化
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ELISA
酶联免疫吸附测定（ELISA）
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可选规格

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100 μg
¥ 7,150.00
选择偶联或无载体版本
免费二抗（20 µl）0/0

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发货Usually dispatched within 2-3 weeks
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