FBW7 (N) Antibody, Rabbit Polyclonal

SKU: orb67185

描述

Rabbit polyclonal to FBW7.F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination andsubsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds tophosphorylated target proteins. FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1released notch intracellular domain (NICD), and probably PSEN1.

研究领域

Epigenetics,Product Categories/Products/Antibodies,Infectious Diseases,Product Categories/Products/Antibodies/Primary Antibodies

图片与验证

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Item 1 of 1

已测应用	WB
稀释范围	WB:1:1000-1:3000
反应性	Human

关键属性

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宿主	Rabbit
克隆性	Polyclonal
免疫原	N-terminal region of human DDB1
分子量	80
纯度	Affinity purification
偶联	Unconjugated

储存与操作

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储存	-20°C
缓冲液/防腐剂	0.01% NaN3
有效期	12 months from date of receipt.
免责声明	For research use only

别名

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anti-FBW7 antibody,anti-Fbox antibody,anti-WD repeatcontaining protein 7 antibody,anti-Archipelago homolog antibody,anti-hAgo antibody,anti-Fbox and WD40 domaincontaining protein 7 antibody,anti-Fbox protein FBX30 antibody,anti-SEL10 antibody,anti-hCdc4 antibody,anti-FBW7 antibody,anti-FBX30 antibody,anti-SEL10 antibody

质量保证

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