Melanoma Associated Antigen KBA.62 Antibody

SKU: orb749955

描述

KBA.62 is a novel anti-melanoma antibody. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. Moreover, it reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes. KBA.62 antibody is useful in identifying malignant melanomas. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, sarcomas, spindle cell carcinomas and various types of mesenchymal neoplasms. A keratin-negative, vimentin-rich neoplasm that immuno-reacts with antibody to S-100 protein and with KBA.62 antibody is, with rare exception, a melanoma. Anti-KBA.62 is a useful additional marker for melanoma, specifically in desmoplastic/spindle cell cases and in the context of micro-metastasis in sentinel lymph node.

研究领域

Product Categories/Products/Antibodies,Product Categories/Products/Antibodies/Primary Antibodies

图片与验证

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Item 1 of 3

已测应用	IF, IHC-P
稀释范围	Immunofluorescence: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT
反应性	Human
应用说明	Optimal dilution of the Melanoma Associated Antigen KBA.62 antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

关键属性

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抗体类型	Primary Antibody
宿主	Mouse
克隆性	Monoclonal
同种型	Mouse IgG1, kappa
克隆号	KBA.62
免疫原	Human KAL cells derived from lymph node metastasis of malignant melanoma were used as the immunogen for the Melanoma Associated Antigen KBA.62 antibody.
纯度	Protein G affinity chromatography
偶联	Unconjugated

储存与操作

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储存	Store the Melanoma Associated Antigen KBA.62 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
缓冲液/防腐剂	0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
有效期	12 months from date of receipt.
危害信息	This Melanoma Associated Antigen KBA.62 antibody is available for research use only.
免责声明	For research use only

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Item 1 of 3
Melanoma Associated Antigen KBA.62 Antibody [orb2639621]
应用：
IF, IHC-P
反应性：
Human
种属/宿主：
Mouse
克隆性：
Monoclonal
偶联：
Unconjugated
可选规格： 100 μg
Item 1 of 2
KBA.62 (Melanoma Associated Antigen) Antibody - With BSA and Azide [orb1789502]
应用：
IF, IHC
反应性：
Human
种属/宿主：
Mouse
克隆性：
Monoclonal
偶联：
Unconjugated
可选规格： 20 μg
Item 1 of 2
KBA.62 (Melanoma Associated Antigen) Antibody [orb389019]
应用：
IF, IHC
反应性：
Human
种属/宿主：
Mouse
克隆性：
Monoclonal
偶联：
Unconjugated
可选规格： 100 μg
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KBA.62 (Melanoma Associated Antigen) Antibody - With BSA and Azide [orb1461570]
应用：
IF, IHC
反应性：
Human
种属/宿主：
Mouse
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Monoclonal
偶联：
Unconjugated
可选规格： 20 μg, 100 μg
KBA.62 (Melanoma Associated Antigen) [orb1945630]
应用：
IHC
反应性：
Human
种属/宿主：
Mouse
克隆性：
Monoclonal
偶联：
Unconjugated
可选规格： 1 ml

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

常用数据库链接

UniProt

Not Known

UniProt 详情

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实验方案信息

IHC-P

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