PD-L1 Antibody / B7-H1 / CD274

SKU: orb2644677

描述

PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancers ability to evade the immune system.

图片与验证

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已测应用	IHC-P, WB
稀释范围	Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT,Western blot: 2-4ug/ml
反应性	Human
应用说明	Optimal dilution of the recombinant PDL1 antibody should be determined by the researcher.

关键属性

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抗体类型	Primary Antibody
宿主	Mouse
克隆性	Recombinant
同种型	Mouse IgG2a, kappa
克隆号	rPDL1/4773
免疫原	A portion of amino acids 39-191 from the human protein was used as the immunogen for the recombinant PDL1 antibody.
纯度	Protein G affinity chromatography
偶联	Unconjugated

储存与操作

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储存	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂	0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide
有效期	12 months from date of receipt.
危害信息	This recombinant PDL1 antibody is available for research use only.
免责声明	For research use only

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IHC-P, WB
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ELISA, FACS, IF
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应用：
IHC-P, WB
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Human
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Recombinant
偶联：
Unconjugated
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质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.