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PD-L1 Antibody / B7-H1 / CD274

SKU: orb699708

描述

PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancers ability to evade the immune system.

研究领域

Product Categories/Products/Antibodies,Product Categories/Research Area,Product Categories/Products/Antibodies/Primary Antibodies,Immunology,Epigenetics

图片与验证

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已测应用IHC-P, WB
稀释范围Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT,Western blot: 2-4ug/ml
反应性Human
应用说明
Optimal dilution of the recombinant PDL1 antibody should be determined by the researcher.

关键属性

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抗体类型Primary Antibody
宿主Mouse
克隆性Recombinant
同种型Mouse IgG2a, kappa
克隆号rPDL1/4773
免疫原A portion of amino acids 39-191 from the human protein was used as the immunogen for the recombinant PDL1 antibody.
纯度Protein G affinity chromatography
偶联Unconjugated

储存与操作

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储存Store the recombinant PDL1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
缓冲液/防腐剂0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide
有效期12 months from date of receipt.
危害信息This recombinant PDL1 antibody is available for research use only.
免责声明For research use only

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质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

UniProt 详情

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暂无 UniProt 数据

实验方案信息

WB
免疫印迹(WB)
查看实验方案
IHC-P
石蜡切片免疫组化
查看实验方案

可选规格

请在下方选择规格

20 μg
¥ 5,330.00
免费二抗(20 µl)0/0

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发货Usually dispatched within 5-10 working days
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