CD44 Antibody / HCAM

SKU: orb640057

描述

Recognizes a cell surface glycoprotein of 80-95kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. This MAb selectively interferes with lymphocyte binding to lymph node, mucosal and synovial endothelium. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

研究领域

Product Categories/Products/Antibodies,Product Categories/Products/Antibodies/Primary Antibodies

图片与验证

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已测应用	FACS, IF, IHC-P, WB
稀释范围	Western blot: 1-2ug/ml,Flow cytometry: 1-2ug/million cells in 0.1ml,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
反应性	Human
应用说明	Optimal dilution of the antibody should be determined by the researcher.

关键属性

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抗体类型	Primary Antibody
宿主	Mouse
克隆性	Recombinant
同种型	Mouse IgG1, kappa
克隆号	rHCAM/918
免疫原	A recombinant full-length human CD44 protein was used as the immunogen for this recombinant CD44 antibody.
纯度	Protein G affinity chromatography
偶联	Unconjugated

储存与操作

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储存	Store the recombinant CD44 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
缓冲液/防腐剂	0.2 mg/ml with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide
有效期	12 months from date of receipt.
危害信息	This recombinant CD44 antibody is available for research use only.
免责声明	For research use only

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FACS, IF, IHC-P, WB
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IF, IHC-P, WB
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Unconjugated
可选规格： 20 μg
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CD44 Antibody / HCAM [orb2639487]
应用：
FACS, IF, IHC-P, WB
反应性：
Human
种属/宿主：
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克隆性：
Monoclonal
偶联：
Unconjugated
可选规格： 100 μg

质量保证

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