NSE Antibody / Neuron Specific Enolase

SKU: orb1825911

描述

This monoclonal antibody recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas.It it be usually employed in combination with other markers such as Synaptophysin,Chromogranin A, and Neurofilament.

图片与验证

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已测应用	IHC-P, WB
稀释范围	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
反应性	Human

关键属性

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抗体类型	Primary Antibody
宿主	Mouse
克隆性	Monoclonal
同种型	Mouse IgG2b, kappa
克隆号	ENO2/4507
免疫原	A recombinant fragment of human NSE gamma (within amino acids 416-433) was used as the immunogen for the Gamma Enolase antibody.
偶联	Unconjugated

储存与操作

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储存	Aliquot the Gamma Enolase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
有效期	12 months from date of receipt.
危害信息	This Gamma Enolase antibody is available for research use only.
免责声明	For research use only

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IHC-P, WB
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质量保证

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常用数据库链接

UniProt

P09104

UniProt 详情

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暂无 UniProt 数据

实验方案信息

免疫印迹（WB）

查看实验方案

IHC-P

石蜡切片免疫组化